Clinical studies have shown that periodontal disease with Aggregatibacter actinomycetemcomitans can exacerbate symptoms of rheumatoid arthritis (RA), but the molecular mechanisms behind this remain ...

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory "autoimmune" response characteristic of ...

Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans), a bacteria linked to gum disease, may worsen rheumatoid arthritis (RA), according to a study published in the International Journal of ...

Researchers from Johns Hopkins Medicine have narrowed down the link between chronic gum disease and rheumatoid arthritis, identifying the common bacterium at play in both conditions. An infection with ...

Researchers at Tokyo Medical and Dental University have found that the periodontal bacterium Aggregatibacter actinomycetemcomitans exacerbates rheumatoid arthritis through inflammasome activation.

In this study, we describe new features of human macrophage cell death induced by A. actinomycetemcomitans leukotoxin that that can be linked to pathogenic mechanisms of inflammatory-related diseases.

Periodontal disease, which affects the gums and tissues that surround the teeth, is one of the most prevalent dental conditions worldwide. Most often caused by the formation and accumulation of ...

Researchers unveil mechanism by which periodontal bacterium A. actinomycetemcomitans exacerbated symptoms of rheumatoid arthritis (RA) conducted various experiments in a mouse model of rheumatoid ...

Tokyo: Periodontal disease, which affects the gums and tissues around the teeth, is one of the most common dental disorders globally. Periodontal disease, which is most commonly caused by the growth ...